The Clearance of the white lesions on the tongue was defined as cure and this was recorded within 24 houses in the patients on Jatropha multifida juice extracts, while those on oral Nystatin showed features of cure at 48 hours. "All the patients randomised to Jatropha multifida therapy were observed to be cured of the oral candida noted lesion 24 hours post single application, while those in Nystatin oral suspension were noted to be cured after 48 hours (eight applications of 100,000 international units each of oral Nystatin). "No side effects were developed in the patients allocated to Nystatin or Jatropha multifida therapy."

Commonly called French physic nut, Spanish physic nut or Coral plant Jatropha multifida belongs to the plant family Euphorbiaceae. Oral candidiasis (thrush) is a fungal infection caused by Candida albicans. This organism is a normal flora and inhabitant of the skin, mouth, vagina and intestinal mucosa. It can be spread to a newborn infant from the mother's birth canal during delivery. Prolonged use of antibiotics, leading to alteration in the oral flora may also cause thrush. The oral lesions are usually white flaky plaques and they may cover all or part of the tongue, lips, gingival and buccal mucous membranes. Oral candidiasis can be acute in the newborn or chronic in children with nutritional deficiencies or debilitating conditions. Nystatin is the most popular choice of antifungal agent used for the treatment of oral fungal infections among general dental practitioners. Conventionally thrush is treated by the oral administration of 100,000 I.U of Nystatin suspension four times a day for seven consecutive days.

The Jatropha multifida is efficacious in the management of oral candidiasis. "Compared to oral Nystatin suspension, it has the advantage of acting faster and being efficacious as a single dose. Its use in the management of oral candidiasis is recommended in third world countries where it is easily cultivated and accessible. "Antibacterial Activity of Jatropha multifida Roots" and hexane, ethyl acetate, chloroform and methanol successive extracts of Jatropha multifida yellow rootbark, red rootbark and rootwood effectively inhibited the growth of Bacillus subtilis and Staphylococcus aureus at concentration of 200 microg/disk. The Encyclopaedia, Useful Plants of Tropical while the leaves and leaf-sap are purgative, but not so violently as of Jatropha curcas. The Antilles of 10-12 leaves lightly cooked and eaten in a salad provide a non-griping purge, but the leaf contains a saponin and an active toxic principle, jatrophin. Leaves and fruit are boiled and taken internally or used externally in a bath as a febrifuge, and an infusion of young leaves is used for most urinary complaints. "Root-bark and roots are ground up as a wound-dressing, and the root is taken internally for worms and, with salt added, for gonorrihoeaa"

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